"Motherless Brooklyn," Edward Norton's second film as a director, has just been chosen to close the New York Film Festival.

Based on the 1999 book by Jonathan Lethem, it follows Lionel Essrog (Norton), a detective with Tourette syndrome, who tries to solve the murder of his mentor and only friend.

The cast for this neo-noir, which is set in the 1950s,  includes Alec Baldwin, Bruce Willis, Willem Dafoe, Gugu Mbatha-Raw,  and Cherry Jones.

The film will make its New York premiere at the Alice Tully Hall on Friday, Oct. 11 and will be released theatrically on November 1.

The film also features a score by Daniel Pemberton, orchestration by Wynton Marsalis and an original song by Thom Yorke.

“Edward Norton has taken Jonathan Lethem’s novel as a jumping-off point to craft a wildly imaginative and extravagant love letter to New York, a beautifully told hard-boiled yarn grounded in the mid-20th-century history of the city. What a way to close the festival,” New York Film Festival director and selection committee chair Kent Jones said in a statement.

Norton said, "To have this particular film – which grew out of my love affair with New York -- selected for Closing Night is just a huge thrill . . . a dream come true, actually.”

He's among good company at this year's NYFF: Martin Scorsese’s "The Irishman” will have its world premiere opening night. And Noah Baumbach’s "Marriage Story" starring Scarlett Johansson and Adam Driver will be the centerpiece film.

“Motherless Brooklyn” will also play the Toronto International Film Festival.

Tickets for the 57th New York Film Festival go on sale to the general public on Sept. 8. Festival and VIP passes are on sale now, including for the closing night.

[Via The Wrap]